Gastroenterology and Hepatology

Microbiome and Its Impact on Colorectal Cancer (CRC)

The human microbiome, which consists of trillions of microorganisms living in and on our body, plays a crucial role in maintaining health and influencing disease development. In recent years, emerging research has uncovered significant links between the microbiome and colorectal cancer (CRC), making it a focus of intensive study in gastroenterology.

Colorectal cancer is one of the most common cancers worldwide, and while genetic factors and lifestyle are well-known contributors, the role of the gut microbiome is gaining increasing attention. The composition of gut bacteria can influence the development of CRC through various mechanisms, such as immune modulation, inflammation, and the metabolism of dietary components.Conversely, a diverse microbiome with a high abundance of protective bacteria, such as those producing butyrate, has been shown to help maintain colon health and may protect against CRC development.

This track will explore the latest research on the gut microbiome’s role in colorectal cancer, including its impact on disease pathogenesis, the potential for microbiome-based diagnostics, and the therapeutic interventions that may arise from this growing field of study. The integration of microbiome research into CRC care has the potential to revolutionize prevention, diagnosis, and treatment, ultimately improving patient outcomes.